Philadelphia - A phase III study associated a once-monthly injection of an atypical antipsychotic with protection against relapse of schizophrenia with a remarkably benign safety profile. The study was conducted on an atypical antipsychotic that has demonstrated a low risk of weight gain and metabolic disturbances relative to other atypical agents. ...

New Orleans - Of the vast number of medications that have been studied in the prevention of migraine, only six have been identified as definitely effective in new guidelines issued jointly by the American Academy of Neurology (AAN) and the American Headache Society (AHS). These included three anticonvulsants, two beta blockers, ...

Review from Published Literature

Bile acid sequestrants were initially developed for the treatment of hypercholesterolemia, but it is significant that essentially all the activity of these agents is confined to the gastrointestinal (GI) tract. The binding of bile acid in the intestine inhibits a key mechanism of cholesterol transport, but the GI applications of ...

Montreal - Patients with inflammatory bowel disease (IBD) often strongly believe psychological stress is a significant factor in the pathogenesis of their disease or in flares, two sets of investigators reported at the 2012 CDDW/CASL meeting. Their findings highlight differences in IBD perception between patients and their physicians that may have ...

San Diego- In patients with heavily pretreated multiple myeloma, clinically important outcomes are being achieved with new therapeutic agents. A number of phase II and III studies presented at the 2011 American Society of Hematology (ASH) meeting suggest that these novel drugs can revive the activity of previously employed agents, leading ...

Chicago - Gout is becoming more common in our aging population and its links to other age-related and life-threatening conditions are increasingly evident. Based on a thorough review of current evidence, new recommendations for gout management, issued at this year’s meeting in preliminary form by the American College of Rheumatology (ACR), ...

Philadelphia - Elevated serum uric acid (SUA) is an important treatable biomarker for renal and cardiovascular (CV) disease, according to data presented at Kidney Week 2011. Elevated SUA was associated with progressive renal disease, increasing rates of CV events, and mortality. These associations persist after controlling for co-morbidities. In one study, ...

David Armstrong, MA, MB BChir, FRCP(UK), FACG, AGAF, FRCPC

Marc Bradette, MD, FRCP

Brian Bressler, MD, MS, FRCPC

Washington, DC - For gastroesophageal reflux disease (GERD), relative acid control is the only meaningful variable for effective therapy. This concept has been blurred by studies that do not distinguish between the sources of upper gastrointestinal (GI) symptoms. Although it is true that pain or discomfort resembling GERD can be ...

Washington, DC - In patients taking oral medications for inflammatory bowel disease (IBD), non-adherence has been remarkably high when considering the serious risks of a significant flare. For the clinician attempting to protect patients from the complications of IBD, strategies to maximize adherence are essential. It is perhaps ironic that ...