{"version":"1.0","provider_name":"The Medical Xchange","provider_url":"https:\/\/themedicalxchange.com\/en\/","title":"Chapter 3: Psoriasis - The Medical Xchange","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"RNnZJdeR0G\"><a href=\"https:\/\/themedicalxchange.com\/en\/review\/2511_chapter-3-psoriasis\/\">Chapter 3: Psoriasis<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/themedicalxchange.com\/en\/review\/2511_chapter-3-psoriasis\/embed\/#?secret=RNnZJdeR0G\" width=\"600\" height=\"338\" title=\"&#8220;Chapter 3: Psoriasis&#8221; &#8212; The Medical Xchange\" data-secret=\"RNnZJdeR0G\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/themedicalxchange.com\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","thumbnail_url":"https:\/\/themedicalxchange.com\/wp-content\/uploads\/2019\/12\/2511_5_Most_Common_Skin_Diseases_Chap_3_Fig1.png","thumbnail_width":960,"thumbnail_height":720,"description":"Psoriasis is a chronic disease characterized by well-demarcated scaly plaques driven by a hyperproliferative epidermis. Although it most commonly involves the scalp, elbows, and knees, it can develop on most skin surfaces, including the palms, soles, and genitalia. Nail involvement is observed in nearly 50% of patients. Total body involvement provides an objective measure of psoriasis severity, but it may not reflect the disease burden for patients self-conscious about lesions or who have persistent pruritus. Common phenotypes include guttate, pustular, annular, erythematous, and palmoplantar forms. The adverse impact of psoriasis on quality of life, including diminished self-esteem, is a well-documented feature.   In Canada, the estimated prevalence of psoriasis is 1.7%, but higher rates have been reported elsewhere. Psoriasis is considered an autoimmune inflammatory process. The most common age of onset is between the ages of 20 and 30 years, although psoriasis can develop in children. Up to 30% of patients also develop inflammation of the joints. Although many of the anti-inflammatory medications effective for psoriasis also reduce disease activity in the joints, psoriatic arthritis is typically managed separately. A variety of disease phenotypes classified by appearance or predominant site of involvement have been described, but psoriasis vulgaris is the most common form of the skin disease."}