{"version":"1.0","provider_name":"The Medical Xchange","provider_url":"https:\/\/themedicalxchange.com\/en\/","title":"Chapter 3: Hyaluronic Acid in Clinical Practice: Managing Symptoms in Knee Osteoarthritis - The Medical Xchange","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"SWHI0jIQCz\"><a href=\"https:\/\/themedicalxchange.com\/en\/review\/solving-osteoarthritis-pain-control-current-stat-3\/\">Chapter 3: Hyaluronic Acid in Clinical Practice: Managing Symptoms in Knee Osteoarthritis<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/themedicalxchange.com\/en\/review\/solving-osteoarthritis-pain-control-current-stat-3\/embed\/#?secret=SWHI0jIQCz\" width=\"600\" height=\"338\" title=\"&#8220;Chapter 3: Hyaluronic Acid in Clinical Practice: Managing Symptoms in Knee Osteoarthritis&#8221; &#8212; The Medical Xchange\" data-secret=\"SWHI0jIQCz\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/themedicalxchange.com\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","thumbnail_url":"https:\/\/themedicalxchange.com\/wp-content\/uploads\/2014\/07\/2506_Knee_OA_Chap_3_EN_Fig_1.PNG","thumbnail_width":960,"thumbnail_height":720,"description":"The therapeutic goals in the management of osteoarthritis (OA) of the knee are to control pain and minimize functional limitations. Treatment is individualized with attention to the immediate objective of pain control while minimizing the risks of the prolonged therapies that may be required to control this chronic condition. Of pharmacologic therapies available for the treatment of knee OA, injection of hyaluronic acid (HA) offers a favorable balance of efficacy and safety. Unlike other conservative treatment options with efficacy against OA pain, such as non-steroidal anti-inflammatory drugs (NSAIDs), localized delivery of HA is associated with a low risk of local or systemic adverse effects. New generation HA therapies, relative to HA formulations introduced in Europe and the United States in the late 1990s, have several relative advantages, including a long duration of effect after a single injection and in some cases a more rapid onset of pain control. Characteristic differences among new generation agents may be further relevant to individualized care in selected patients."}